Analysis of EEG Coherence During Active Suppression in Patients with Tourette’s Syndrome

Kalusche, William (2018) Analysis of EEG Coherence During Active Suppression in Patients with Tourette’s Syndrome. Undergraduate thesis, under the direction of Dwight Waddell from Biomedical Engineering, The University of Mississippi.


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One of the first studies that investigated quantitative qualities of Tourette syndrome (TS) found that during active suppression of tics TS patients exhibit increased coherence in the alpha frequency (Serrien, Orth, Evans, Lees, & Brown, 2005). In this study, we attempted to validate the previous literature to allow for future research into the role played by increased coherence during active suppression. Our findings,however, showed that there was no significant increase in coherence between active suppression and rest. The findings in this study, along with previous literature, may suggest that TS patients with comorbid obsessive-compulsive disorder (OCD) affect the alpha power seen in these individuals. This finding shows that coherence may not increase in all TS patients as previously thought, but instead may increase only in individuals with pure TS. These findings show that further research, with a larger sample size, will be needed to determine the effects of comorbid OCD on the change in coherence during active suppression.

Item Type: Thesis (Undergraduate)
Creators: Kalusche, William
Student's Degree Program(s): B.S.E. Engineering
Thesis Advisor: Dwight Waddell
Thesis Advisor's Department: Biomedical Engineering
Institution: The University of Mississippi
Subjects: T Technology > TA Engineering (General). Civil engineering (General)
Depositing User: William Kalusche
Date Deposited: 18 May 2018 15:17
Last Modified: 18 May 2018 15:17

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