The Olfactory System in Schizophrenia: an rsfMRI Study of the Piriform Cortex

Kiparizoska, Sara (2016) The Olfactory System in Schizophrenia: an rsfMRI Study of the Piriform Cortex. Undergraduate thesis, under the direction of Tossi Ikuta from Communication Sciences and Disorders, University of Mississippi.

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Abstract

This thesis is a study of rsfMRI imaging in order to examine coactivation patters of the piriform cortex between healthy subjects and people with schizophrenia. As part of the olfactory system, the piriform cortex is an integral part of the smell sensation. Our studies showed that coactivation among the piriform cortex and other sensory brain regions differ in people with schizophrenia compared to healthy subjects. People with schizophrenia exhibit patterns of less coactivation among their sensory brain regions compared to control subjects, specifically the intracalcarine cortex, the right planum temporale, and the left occipital lobe. The purpose of this study is to gain a better understanding of schizophrenia functionality. Further studies of these results could be used to create novel therapies or identify new markers for schizophrenia.

Item Type: Thesis (Undergraduate)
Creators: Kiparizoska, Sara
Student's Degree Program(s): B.A. Biochemistry
Thesis Advisor: Tossi Ikuta
Thesis Advisor's Department: Communication Sciences and Disorders
Institution: University of Mississippi
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Depositing User: Miss Sara Kiparizoska
Date Deposited: 13 May 2016 13:04
Last Modified: 13 May 2016 13:04
URI: http://thesis.honors.olemiss.edu/id/eprint/538

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